Management of traumatic brain injury: some current evidence and applications

Postgrad Med J. 2004 Nov;80(949):650-3. doi: 10.1136/pgmj.2004.019570.

Abstract

Traumatic brain injury remains a worldwide problem. Newer modalities in the management of such injuries include both drugs and therapeutic strategies. Continuing research in animal models has provided a better understanding of the pathophysiological processes that follow head injury, and this in turn has enabled workers to work on improved treatment targets. Although there are exciting and novel approaches emerging, there is no substitute for meticulous initial resuscitation. Additionally, some of the more well known management options are now better understood. These concepts are discussed in the article.

Publication types

  • Review

MeSH terms

  • Absorptiometry, Photon
  • Anti-Inflammatory Agents / therapeutic use
  • Barbiturates / therapeutic use
  • Brain Injuries / etiology
  • Brain Injuries / therapy*
  • Clinical Trials as Topic
  • Diuretics, Osmotic / therapeutic use
  • Dronabinol / analogs & derivatives*
  • Dronabinol / therapeutic use
  • Humans
  • Hydrostatic Pressure
  • Hypothermia / therapy
  • Mannitol / therapeutic use
  • Neuromuscular Blockade
  • Neuroprotective Agents / therapeutic use
  • Osmotic Pressure
  • Sodium Chloride / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Barbiturates
  • Diuretics, Osmotic
  • Neuroprotective Agents
  • Mannitol
  • Sodium Chloride
  • Dronabinol
  • HU 211