Biomimetic synthesis of the pyrrolobenzoxazine core of paeciloxazine

Chem Commun (Camb). 2004 Nov 21:(22):2552-3. doi: 10.1039/b412300j. Epub 2004 Oct 25.

Abstract

Starting from a protected L-tryptophan derivative the pyrrolobenzoxazine core unit of paeciloxazine can be synthesized in two oxidation steps.

MeSH terms

  • Antinematodal Agents / chemical synthesis*
  • Benzoxazines / chemical synthesis*
  • Models, Chemical
  • Molecular Structure
  • Oxazines / chemistry*

Substances

  • Antinematodal Agents
  • Benzoxazines
  • Oxazines
  • paeciloxazine