Application of adaptive filters to visual testing and treatment in acquired pendular nystagmus

J Rehabil Res Dev. 2004 May;41(3A):313-24. doi: 10.1682/jrrd.2003.03.0042.

Abstract

Acquired pendular nystagmus (APN) complicates multiple sclerosis and other neurological disorders, causes visual impairment, and frequently resists treatment. Vision could be improved by a visual aid that gates or shifts the seen world in lockstep with the APN. Since the pathological oscillations are embedded in normal eye movements, such a device must track the nystagmus selectively. We evaluated the ability of an adaptive filter to perform this tracking and improve acuity when coupled to either of two devices--a shutter that permitted brief glimpses of the world synchronized with the nystagmus, or simulated image-shifting optics. In 10 normal subjects whose decimal acuity averaged 1.46 +/- 0.20, acuity fell to 0.36 +/- 0.08 under viewing conditions simulating APN. The synchronized shutter restored acuity to 0.60 +/- 0.12, while image-stabilization raised it to 1.17 +/- 0.13. Adaptive filters provide a practical means by which to track nystagmus. The most effective visual aid would couple such filters to image-stabilizing optics.

Publication types

  • Clinical Trial
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adaptation, Physiological / physiology
  • Adult
  • Algorithms
  • Humans
  • Least-Squares Analysis
  • Lenses*
  • Middle Aged
  • Nystagmus, Pathologic / physiopathology
  • Nystagmus, Pathologic / rehabilitation*
  • Oscillometry / instrumentation*
  • Signal Processing, Computer-Assisted*
  • Visual Acuity / physiology*