Hormonal monitoring of the first trimester of pregnancy

Obstet Gynecol Clin North Am. 2004 Dec;31(4):767-78, x. doi: 10.1016/j.ogc.2004.08.004.

Abstract

The hormonal changes and maternal adaptations of human pregnancy are among the most remarkable phenomena in nature. Endocrinologic parameters in the early gestation period have been used to predict abnormal pregnancies and to identify fetuses that have chromosomal aberrations. This article focuses on the changes in hormones that are secreted by the maternal-fetal-placental unit that are unique for the first trimester of pregnancy and their impact on clinical outcome.

Publication types

  • Review

MeSH terms

  • Carcinoembryonic Antigen / metabolism
  • Cytokines / metabolism
  • Female
  • Growth Differentiation Factor 15
  • Hormones / metabolism*
  • Humans
  • Insulin-Like Growth Factor Binding Protein 1 / metabolism
  • Macrophage Migration-Inhibitory Factors / metabolism
  • Pregnancy / metabolism*
  • Pregnancy Trimester, First / physiology*
  • Pregnancy-Associated Plasma Protein-A / metabolism

Substances

  • Carcinoembryonic Antigen
  • Cytokines
  • GDF15 protein, human
  • Growth Differentiation Factor 15
  • Hormones
  • Insulin-Like Growth Factor Binding Protein 1
  • Macrophage Migration-Inhibitory Factors
  • Pregnancy-Associated Plasma Protein-A