Steroid hormone synthesis in pregnancy

Obstet Gynecol Clin North Am. 2004 Dec;31(4):795-816, x. doi: 10.1016/j.ogc.2004.08.009.


The goal of this article is to summarize what is known about the pathways of steroid hormone synthesis and metabolism in human pregnancy. Emphasis is placed on the distinctions between steroidogenic pathways in adults and those that are operative during human pregnancy.

Publication types

  • Review

MeSH terms

  • Animals
  • Cholesterol / metabolism
  • Cholesterol Side-Chain Cleavage Enzyme / metabolism
  • Dehydroepiandrosterone Sulfate / metabolism
  • Female
  • Humans
  • Molecular Structure
  • Placenta / metabolism
  • Pregnancy
  • Steroids / biosynthesis*
  • Steroids / chemistry


  • Steroids
  • Dehydroepiandrosterone Sulfate
  • Cholesterol
  • Cholesterol Side-Chain Cleavage Enzyme