Epidemiology of urticaria in Spain

J Investig Allergol Clin Immunol. 2004;14(3):214-20.


Background: In spite of the frequency of chronic urticaria there are very few epidemiological studies of its prevalence and distribution.

Objective: We wanted to approach the real prevalence of chronic urticaria in a population-based study and to depict demographic distribution and personal perception of the disease. We also wanted to describe the frequency of acute urticaria episodes in the population studied.

Methods: We conducted a population-based study among adults in Spain. We questioned 5003 individuals after calculating a sample size for a maximum variability (conservative approach p=q=0.5).

Results: We found a 0.6% (95% CI: 0.4-0.8) prevalence of chronic urticaria. The prevalence is significantly higher in women than in men with a OR=3.82 (95%CI 1.56-9.37). Chronic urticaria is a self-limited disease, yet in 8.7% of cases chronic urticaria lasts from one to 5 years and in 11.3%, for more than 5 years. The average age of onset is 40 years.

Conclusions: We offer large epidemiology study data on the prevalence of chronic urticaria. The prevalence of chronic urticaria has not yet been defined in an adult population-based study. With this work we offer such data to describe the prevalence and features of this disease.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Chronic Disease
  • Confidence Intervals
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Probability
  • Prognosis
  • Severity of Illness Index
  • Sex Distribution
  • Skin Tests
  • Spain / epidemiology
  • Surveys and Questionnaires
  • Urticaria / epidemiology*
  • Urticaria / immunology*