Members of the genera Paenibacillus and Rhodococcus harbor genes homologous to enterococcal glycopeptide resistance genes vanA and vanB

L Guardabassi; H Christensen; H Hasman; A Dalsgaard

doi:10.1128/AAC.48.12.4915-4918.2004

Members of the genera Paenibacillus and Rhodococcus harbor genes homologous to enterococcal glycopeptide resistance genes vanA and vanB

Antimicrob Agents Chemother. 2004 Dec;48(12):4915-8. doi: 10.1128/AAC.48.12.4915-4918.2004.

Authors

L Guardabassi¹, H Christensen, H Hasman, A Dalsgaard

Affiliation

¹ Department of Veterinary Pathobiology, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark. lg@kvl.dk

Abstract

Genes homologous to enterococcal glycopeptide resistance genes vanA and vanB were found in glycopeptide-resistant Paenibacillus and Rhodococcus strains from soil. The putative D-Ala:D-Lac ligase genes in Paenibacillus thiaminolyticus PT-2B1 and Paenibacillus apiarius PA-B2B were closely related to vanA (92 and 87%) and flanked by genes homologous to vanH and vanX in vanA operons.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteria / genetics*
Bacterial Proteins / genetics*
Carbon-Oxygen Ligases / genetics*
Drug Resistance, Bacterial
Enterococcus / genetics*
Molecular Sequence Data
Operon / genetics
Reverse Transcriptase Polymerase Chain Reaction
Rhodococcus / genetics*
Soil Microbiology

Substances

Bacterial Proteins
VanA ligase, Bacteria
Carbon-Oxygen Ligases

Associated data

GENBANK/AY648035
GENBANK/AY648036
GENBANK/AY648697
GENBANK/AY648698