Brain perfusion territory imaging applying oblique-plane arterial spin labeling with a standard send/receive head coil

Magn Reson Med. 2004 Dec;52(6):1443-7. doi: 10.1002/mrm.20253.


A new method for the selective spin labeling of left- or right-sided supplying arteries of the brain without the need for additional RF coils is demonstrated. A clinical 1.5 T scanner was used. The spatial selectivity of the labeling process is based on the limited coverage of the excitation field of a standard send/receive head coil together with an oblique positioning of the labeling plane. A computer simulation was used to optimize key labeling parameters under the condition of laminar flow. The validity of the computer model results was confirmed by MRI measurements with a flow model. For human studies, a double-inversion continuous arterial spin labeling (CASL) sequence was modified to allow for arbitrary positioning of the labeling plane. The obtained perfusion-weighted images showed a clear delineation of the perfusion territories of the selected arteries in the anterior circulation of the brain and good gray/white matter contrast.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Mapping*
  • Cerebrovascular Circulation*
  • Computer Simulation
  • Humans
  • Magnetic Resonance Imaging / instrumentation*
  • Phantoms, Imaging
  • Spin Labels*


  • Spin Labels