Does the primary Lung Cancer rate increase among females?

Bull Cancer. 2004 Jun;91(6):E201-10.

Abstract

Lung cancer is still the most frequently seen malignancy among males where as females are less affected. Recently the lung cancer prevalence has been reported to increase among females in parallel to the increment in cigarette consumption. In our 2 clinic 11.2% (44 cases) of 393 primary lung cancer cases between 1993-1997 were female. We evaluated the demographical characteristics and yearly distribution of our female patients. Mean age was 64+/-12.1 and 18.2% of the patients were smokers. The main complaints were dyspnoea (59%), chest pain (57%), fatigue (47%), cough (45%)and sputum production (32%). The cell type distribution rates were as follows;adenocarcinoma 45.4%, squamous cell cancer 29.5%, small cell cancer 20.5% and large cell cancer 4.6%. The diagnostic methods used were sputum cytology (27.3%),transbronchial biopsy and lavage (38.6%), thoracocentesis and pleural biopsy (15.8%),transthoracic fine needle aspiration (13,6%) and open lung biopsy (4.7%). As a result,we found a low percentage of smokers but a high rate of adenocarcinomas among our female patients.

MeSH terms

  • Adenocarcinoma / epidemiology
  • Adenocarcinoma / pathology
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy
  • Carcinoma, Large Cell / epidemiology
  • Carcinoma, Large Cell / pathology
  • Carcinoma, Small Cell / epidemiology
  • Carcinoma, Small Cell / pathology
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / pathology
  • Female
  • Humans
  • Incidence
  • Lung / pathology
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / pathology
  • Male
  • Middle Aged
  • Sex Distribution
  • Smoking / epidemiology