Choroid plexus adenoma: case report and review of the literature

Childs Nerv Syst. 2005 May;21(5):410-5. doi: 10.1007/s00381-004-1038-8. Epub 2004 Nov 25.

Abstract

Case report: An 8-month-old infant with macrocephaly was found to have hydrocephalus and a cystic third ventricular tumour; biopsy of the tumour showed a choroid plexus adenoma. The tumour was attached to the ependymal lining and was strongly adherent to the walls and floor of the anterior third ventricle.

Treatment: After biopsy, it was felt that a radical resection would carry a high risk of injury to the floor of the third ventricle and cause new neurological deficits. Therefore, an external ventricular drain was inserted and bilateral ventriculo-peritoneal shunts were inserted 1 week post-operatively. In view of the benign nature of the tumour, no adjuvant radiotherapy or chemotherapy was given.

Outcome: There was no further tumour growth or clinical deterioration over a 6-year follow-up period.

Publication types

  • Case Reports
  • Comparative Study
  • Review

MeSH terms

  • Adenoma* / complications
  • Adenoma* / metabolism
  • Adenoma* / surgery
  • Choroid Plexus Neoplasms* / complications
  • Choroid Plexus Neoplasms* / metabolism
  • Choroid Plexus Neoplasms* / surgery
  • Follow-Up Studies
  • Humans
  • Hydrocephalus / complications
  • Hydrocephalus / metabolism
  • Hydrocephalus / surgery
  • Immunohistochemistry / methods
  • Infant
  • Magnetic Resonance Imaging / methods
  • Male
  • Prealbumin / metabolism
  • S100 Proteins / metabolism
  • Ventriculoperitoneal Shunt / methods
  • Vimentin / metabolism

Substances

  • Prealbumin
  • S100 Proteins
  • Vimentin