Pregnancy outcome in women with rheumatoid arthritis before disease onset

J Rheumatol. 1992 Jan;19(1):18-21.


Pregnancy outcome before disease onset was evaluated for women with rheumatoid arthritis (RA) and control women as part of a prospective case-control study of newly diagnosed RA. An analysis of women who were ever gravid revealed no statistically significant difference in any adverse pregnancy outcome between RA cases (n = 144) and controls (n = 605) including spontaneous abortions and stillbirths. Thus, in contrast to reports both of an increase of adverse pregnancy outcomes and a decrease in women who subsequently develop RA, we found no evidence for any difference in pregnancy outcome in the RA group.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abortion, Spontaneous
  • Adolescent
  • Adult
  • Arthritis, Rheumatoid / ethnology
  • Arthritis, Rheumatoid / physiopathology*
  • Case-Control Studies
  • Continental Population Groups
  • Female
  • Humans
  • Middle Aged
  • Minority Groups
  • Pregnancy
  • Pregnancy Complications*
  • Pregnancy Outcome*
  • Prospective Studies