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, 75 (7-8), 740-4

Anti-inflammatory and Antinociceptive Activities of Trewia Polycarpa Roots

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Anti-inflammatory and Antinociceptive Activities of Trewia Polycarpa Roots

D Chamundeeswari et al. Fitoterapia.

Abstract

The alcoholic extract of Trewia polycarpa roots, when administered orally to rats at doses of 50-400 mg/kg, exhibited a dose-dependent anti-inflammatory activity in both acute and chronic models. It also showed a significant antinociceptive action mice in the dose range of 25-200 mg/kg. The extract did not reveal any toxicity in rats up to a dose of 3.2 g/kg (p.o.). It showed the presence of terpenoids, alkaloids, flavonoids, quinones and glycosides on phytochemical screening.

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