Analyzing the mosaic structure of genes

J Mol Evol. 1992 Feb;34(2):126-9. doi: 10.1007/BF00182389.


Some genes in prokaryotes consist of a mosaic of regions derived from different ancestors by horizontal gene transfer. A method is described for demonstrating the statistical significance of such mosaic structure and for locating the crossover points separating different regions.

Publication types

  • Review

MeSH terms

  • Chi-Square Distribution
  • Crossing Over, Genetic*
  • Genes, Bacterial*
  • Mosaicism / genetics*
  • Transformation, Bacterial