Treatment and prevention of rickettsial and ehrlichial infections

Dermatol Ther. 2004;17(6):499-504. doi: 10.1111/j.1396-0296.2004.04052.x.


Rickettsial and ehrlichial infections are both carried by arthropod vectors. Both Rickettsia and Ehrlichia are small intracellular gram-negative coccobacilli. Clinical manifestations of Rickettsia range from spotted fevers to various forms of typhus. Human ehrlichiosis can present as monocytic ehrlichiosis or granulocytic anaplasmosis. Prevention is by avoidance of the responsible vectors. Therapy is usually with doxycycline, but chloramphenicol can also be used.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use*
  • Doxycycline / therapeutic use*
  • Ehrlichia / pathogenicity
  • Ehrlichiosis / drug therapy*
  • Ehrlichiosis / prevention & control
  • Humans
  • Rickettsia / pathogenicity
  • Rickettsia Infections / drug therapy*
  • Rickettsia Infections / prevention & control


  • Anti-Bacterial Agents
  • Doxycycline