[New russian myorelaxant vero-pipecuronium (pipecuronium bromide) used for the anesthetic management of operations on the thorax and abdomen organs]

Anesteziol Reanimatol. 2004 Sep-Oct:(5):49-52.
[Article in Russian]

Abstract

The experience of clinical use of the new Russian myorelaxant of the non-depolarizing action vero-pipecuronium (pipecuronium bromided) manufactured by "Veropharm" is described. Vero-pipecuronium was found to ensure splendid and good conditions for the intubation of the trachea and to maintain reliably myorelaxation. The recommended doses and availability of an antidote (prozerine) provide for a sufficiently controllable myorelaxation. Vero-pipecuronium does not virtually exert any effect on the parameters of hemodynamics and can be successfully used in patients with a high anesthetic risk including heart surgeries. Thus, Russian vero-pipecuronium has now an effective and safe myorelaxant manufactured inside the country, whose parameters are not inferior to those of pipecuronium bromide (arduan) manufactured by "Gedeon Richter", Hungary. Since the described drug is made in Russia, one can hope it will be highly effective both economically and pharmacologically.

Publication types

  • English Abstract

MeSH terms

  • Abdomen / surgery*
  • Adult
  • Aged
  • Aged, 80 and over
  • Anesthesia, General*
  • Hemodynamics / drug effects
  • Humans
  • Intubation, Intratracheal
  • Middle Aged
  • Monitoring, Intraoperative
  • Muscle Relaxation / drug effects*
  • Neuromuscular Nondepolarizing Agents / administration & dosage
  • Neuromuscular Nondepolarizing Agents / therapeutic use*
  • Pipecuronium / administration & dosage
  • Pipecuronium / therapeutic use*
  • Thoracic Surgery / methods*

Substances

  • Neuromuscular Nondepolarizing Agents
  • Pipecuronium