Studies on the anti-inflammatory, antipyretic and analgesic properties of the leaves of Aegle marmelos Corr

J Ethnopharmacol. 2005 Jan 4;96(1-2):159-63. doi: 10.1016/j.jep.2004.09.013.

Abstract

The serial extracts of the leaves of Aegle marmelos Corr. were investigated for anti-inflammatory property. The analgesic and antipyretic properties were also evaluated. The most of the extracts derived from the plant Aegle marmelos caused a significant inhibition of the carrageenan-induced paw oedema and cotton-pellet granuloma in rats. The extracts also produced marked analgesic activity by reduction the early and late phases of paw licking in mice. A significant reduction in hyperpyrexia in rats was also produced by the most of the extracts. This study was established anti-inflammatory, antinociceptive and antipyretic activities of the leaves of Aegle marmelos.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetic Acid
  • Aegle*
  • Analgesics, Non-Narcotic / pharmacology
  • Analgesics, Non-Narcotic / therapeutic use*
  • Animals
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use*
  • Behavior, Animal / drug effects
  • Carrageenan
  • Edema / chemically induced
  • Edema / drug therapy
  • Fever / drug therapy
  • Fever / etiology
  • Granuloma / chemically induced
  • Granuloma / drug therapy
  • Male
  • Pain / chemically induced
  • Pain / drug therapy
  • Phytotherapy*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Plant Leaves / chemistry
  • Rats
  • Rats, Wistar
  • Yeasts

Substances

  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents
  • Plant Extracts
  • Carrageenan
  • Acetic Acid