CARHTA GENE: multipopulation integrated genetic and radiation hybrid mapping

Bioinformatics. 2005 Apr 15;21(8):1703-4. doi: 10.1093/bioinformatics/bti222. Epub 2004 Dec 14.

Abstract

CAR(H)(T)A GENE: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. CAR(H)(T)A GENE: performs multipoint maximum likelihood estimations with accelerated expectation-maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. CAR(H)(T)A GENE: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated.

Availability: The program is available free of charge from www.inra.fr/bia/T/CarthaGene for Linux, Windows and Solaris machines (with Open Source).

Contact: tschiex@toulouse.inra.fr.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Mapping / methods
  • Computer Graphics
  • Computer Simulation
  • Crosses, Genetic*
  • Genetics, Population*
  • Models, Genetic*
  • Models, Statistical
  • Radiation Hybrid Mapping / methods*
  • Software*
  • User-Computer Interface*