Significant responses to platinum-based chemotherapy in renal medullary carcinoma

Pediatr Blood Cancer. 2005 Apr;44(4):407-11. doi: 10.1002/pbc.20292.

Abstract

Most patients with renal medullary carcinoma (RMC) have advanced disease at presentation and rarely respond to radiation or chemotherapy. We describe two adolescents with metastatic disease who had significant responses to cisplatin or carboplatin in combination with gemcitabine and paclitaxel.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • African Americans
  • Anemia, Sickle Cell / complications
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carboplatin / administration & dosage
  • Carboplatin / therapeutic use*
  • Carcinoma, Renal Cell / complications
  • Carcinoma, Renal Cell / drug therapy*
  • Cisplatin / administration & dosage
  • Cisplatin / therapeutic use*
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives*
  • Female
  • Humans
  • Kidney Medulla*
  • Kidney Neoplasms / complications
  • Kidney Neoplasms / drug therapy*
  • Male
  • Paclitaxel / administration & dosage
  • Treatment Outcome

Substances

  • Deoxycytidine
  • gemcitabine
  • Carboplatin
  • Paclitaxel
  • Cisplatin