Extracellular matrix and visual cortical plasticity: freeing the synapse

Nicoletta Berardi; Tommaso Pizzorusso; Lamberto Maffei

doi:10.1016/j.neuron.2004.12.008

Extracellular matrix and visual cortical plasticity: freeing the synapse

Neuron. 2004 Dec 16;44(6):905-8. doi: 10.1016/j.neuron.2004.12.008.

Authors

Nicoletta Berardi¹, Tommaso Pizzorusso, Lamberto Maffei

Affiliation

¹ Istituto Neuroscienze CNR, Via G. Moruzzi 1, 56100 Pisa, Italy.

PMID: 15603733
DOI: 10.1016/j.neuron.2004.12.008

Abstract

The effects of monocular deprivation (MD) on the ocular dominance of visual cortical neurons are a paradigmatic example of experience-dependent plasticity. Here we review recent data showing that extracellular matrix (ECM) plays an important role in the control of experience-dependent plasticity both in the developing and adult visual cortex.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Extracellular Matrix / physiology*
Humans
Neuronal Plasticity / physiology*
Synapses / metabolism*
Visual Cortex / physiology*