Getting it wrong: the clinical misdiagnosis of Alzheimer's disease

Int J Clin Pract. 2004 Nov;58(11):1092-4. doi: 10.1111/j.1368-5031.2004.00314.x.


Two patients whose diagnosis of Alzheimer's disease proved to be incorrect on follow-up are presented. Factors which contributed to the misdiagnosis included failure to obtain collateral history, failure to apply widely accepted diagnostic criteria, over-reliance on structural brain imaging and lack of longitudinal follow-up. Analysis of diagnostic errors may permit avoidance of similar pitfalls in future.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alzheimer Disease / diagnosis*
  • Atrophy / diagnosis
  • Brain / pathology
  • Brain Injuries / diagnosis
  • Diagnostic Errors*
  • Female
  • Humans
  • Male
  • Medical History Taking / standards
  • Middle Aged