Sources of carbon which decrease the specific activity of [11C]CH3I synthesized by the single pass I2 method

Ming-Rong Zhang; Kazutoshi Suzuki

doi:10.1016/j.apradiso.2004.07.003

Sources of carbon which decrease the specific activity of [11C]CH3I synthesized by the single pass I2 method

Appl Radiat Isot. 2005 Mar;62(3):447-50. doi: 10.1016/j.apradiso.2004.07.003.

Authors

Ming-Rong Zhang¹, Kazutoshi Suzuki

Affiliation

¹ Department of Medical Imaging, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.

PMID: 15607922
DOI: 10.1016/j.apradiso.2004.07.003

Abstract

The sources of carbon, which decrease the specific activity of [11C]Methyl iodide [11C]CH3I synthesized by the single pass I2 method were, determined. Some organic solvents (acetone, CH3OH and THF etc.) and non-volatile oils (silicone oil and paraffin) could react with the I2 vapor to yield the non-radioactive CH3I in the heated quartz tube, which decreased the specific activity of [11C]CH3I significantly.