A Protein Which Specifically Binds to Single Stranded TTAGGGn Repeats

Nucleic Acids Res. 1992 Mar 25;20(6):1387-91. doi: 10.1093/nar/20.6.1387.

Abstract

Nuclei from tissues of many vertebrates contain a soluble 37 kd protein which binds with a high degree of specificity to oligonucleotides which contain the G rich strand of the telomeric terminal repeats, TTAGGG. In some tissues this is an abundant nuclear protein.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • DNA, Single-Stranded / metabolism*
  • DNA-Binding Proteins / isolation & purification
  • DNA-Binding Proteins / metabolism*
  • Electrophoresis, Polyacrylamide Gel
  • Mice
  • Molecular Sequence Data
  • Repetitive Sequences, Nucleic Acid*
  • Species Specificity
  • Telomere / metabolism

Substances

  • DNA, Single-Stranded
  • DNA-Binding Proteins