Acute anterior uveitis and spondyloarthropathies

Rheum Dis Clin North Am. 1992 Feb;18(1):143-51.


An acute onset, unilateral anterior uveitis occurs during the course of either Reiter's syndrome or ankylosing spondylitis. Conversely, many patients who suffer from an acute anterior uveitis are HLA-B27-positive and have associated joint disease. The consistent presentation of the uveitis can aid in the process of differential diagnosis. This article includes a discussion of the recognition of the characteristic presentation, the complications, the role of B27 testing, the relevance of animal models, the pathogenesis, and treatment.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acute Disease
  • Diagnosis, Differential
  • HLA-B27 Antigen / analysis
  • Humans
  • Spinal Diseases / complications*
  • Steroids / therapeutic use
  • Uveitis, Anterior / complications*
  • Uveitis, Anterior / diagnosis
  • Uveitis, Anterior / immunology


  • HLA-B27 Antigen
  • Steroids