[Therapy for chronic radial epicondylitis with botulinum toxin A]

Z Orthop Ihre Grenzgeb. 2004 Nov-Dec;142(6):701-5. doi: 10.1055/s-2004-832407.
[Article in German]

Abstract

Aim: Chronic radial epicondylitis (tennis elbow) is not a serious disease but patients may suffer greatly. If standard conservative and possibly operative treatment modalities have not been effective, patients need further therapy. First trials with injection of Botulinum toxin A (Btx A) have shown promising results. The purpose of the study was to clarify if a single injection of Btx A could be an efficient therapy for chronic radial epicondylitis.

Methods: In this study 16 patients received injections into the forearm extensors. The site of injection was determined by local tenderness and pain provocation on finger and wrist extension.

Results: A significant clinical improvement was already seen at 2 weeks following injection. The effect was noted up to the last follow-up at 2 years. Continuous and maximal pain during the last 48 h, as self-assessed on a visual analogue scale, was also significantly reduced. In a few cases a significant decrease of muscle strength was seen for the third finger two weeks after injection. It slowly returned thereafter.

Conclusion: A single injection of Btx A was effective as therapy for chronic tennis elbow. It can be carried out in an out-patient setting, and allows the patient to continue working.

Publication types

  • English Abstract

MeSH terms

  • Ambulatory Care
  • Botulinum Toxins, Type A / administration & dosage*
  • Chronic Disease
  • Follow-Up Studies
  • Hand Strength
  • Humans
  • Image Processing, Computer-Assisted
  • Injections, Intramuscular
  • Magnetic Resonance Imaging
  • Pain Measurement
  • Tennis Elbow / diagnosis
  • Tennis Elbow / drug therapy*
  • Treatment Outcome

Substances

  • Botulinum Toxins, Type A