Electronic nose prediction of a clinical pneumonia score: biosensors and microbes

Anesthesiology. 2005 Jan;102(1):63-8. doi: 10.1097/00000542-200501000-00013.


Background: The authors performed a prospective study to determine whether breath test analysis using an electronic nose correlates with a clinical pneumonia score.

Methods: Exhaled gas was sampled from the expiratory limb of the ventilator in mechanically ventilated surgical intensive care patients and assayed with the electronic nose. Components of a clinical pneumonia score were recorded concurrently.

Results: The score predicted by the electronic nose showed good correlation with the actual pneumonia score (r = 0.81). Bland Altman analysis showed a mean bias of 0.0 (limits +/- 2.6).

Conclusions: The electronic nose is a new biosensor technology that correlates with a clinical pneumonia score.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Biosensing Techniques*
  • Female
  • Humans
  • Intubation, Intratracheal
  • Male
  • Middle Aged
  • Pneumonia / diagnosis*
  • Pneumonia / microbiology*
  • Pneumonia / physiopathology
  • Positive-Pressure Respiration
  • Respiration, Artificial / adverse effects*