The Arabidopsis thaliana MEDEA Polycomb group protein controls expression of PHERES1 by parental imprinting

Nat Genet. 2005 Jan;37(1):28-30. doi: 10.1038/ng1495. Epub 2004 Dec 26.


The maternally expressed Arabidopsis thaliana Polycomb group protein MEDEA (MEA) controls expression of the MADS-box gene PHERES1 (PHE1). Here, we show that PHE1 is mainly paternally expressed but maternally repressed and that this maternal repression of PHE1 breaks down in seeds lacking maternal MEA activity. Because Polycomb group proteins control parental imprinting in mammals as well, the independent recruitment of similar protein machineries for the imprinting of genes is a notable example of convergent evolution.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / metabolism
  • Arabidopsis Proteins / genetics*
  • Arabidopsis Proteins / metabolism*
  • Gene Expression Regulation, Plant / physiology*
  • Genomic Imprinting / physiology*
  • MADS Domain Proteins / genetics*
  • MADS Domain Proteins / metabolism
  • Polycomb-Group Proteins
  • Repressor Proteins / metabolism


  • Arabidopsis Proteins
  • MADS Domain Proteins
  • MEA protein, Arabidopsis
  • PHERES1 protein, Arabidopsis
  • Polycomb-Group Proteins
  • Repressor Proteins