Abstract
In this issue of Cell, the Hall group describes how the rapamycin-sensitive TOR signaling network controls ribosomal protein (RP) gene expression via the Forkhead-like transcription factor FHL1 in budding yeast (Martin et al., 2004). These findings represent a crucial advance in our understanding of the mechanism by which TOR regulates ribosome biogenesis in response to environmental cues.
MeSH terms
-
Forkhead Transcription Factors
-
Gene Expression Regulation, Fungal*
-
Nuclear Proteins / metabolism*
-
Phosphatidylinositol 3-Kinases / metabolism*
-
Phosphotransferases (Alcohol Group Acceptor) / metabolism*
-
Repressor Proteins / genetics
-
Repressor Proteins / metabolism
-
Ribosomal Proteins / genetics
-
Ribosomal Proteins / metabolism
-
Ribosomes / metabolism*
-
Saccharomyces cerevisiae / genetics*
-
Saccharomyces cerevisiae / metabolism*
-
Saccharomyces cerevisiae Proteins / metabolism*
-
Transcription Factors / metabolism*
Substances
-
Forkhead Transcription Factors
-
Nuclear Proteins
-
Repressor Proteins
-
Ribosomal Proteins
-
Saccharomyces cerevisiae Proteins
-
Transcription Factors
-
Phosphotransferases (Alcohol Group Acceptor)
-
TOR1 protein, S cerevisiae