The phenogenetic logic of life
- PMID: 15630420
- DOI: 10.1038/nrg1502
The phenogenetic logic of life
Abstract
For nearly a century we have understood that life works through genes, and so have had an elegant theory for general evolution. But this did not explain the kinds of traits that characterize organisms, nor how genes produce them. Advances in recent decades have opened the way for an understanding of the phenogenetic logic or relational principles of life, by which a few basic characteristics of genomes produce biological phenotypes through some basic developmental processes. This logic provides a general explanation of the nature and source of organismal design, and a powerful programme for research.
Similar articles
-
Contributions of genomics to life-history theory.Nat Rev Genet. 2007 Feb;8(2):116-25. doi: 10.1038/nrg2040. Nat Rev Genet. 2007. PMID: 17230198 Review.
-
On the gradual evolution of complexity and the sudden emergence of complex features.Artif Life. 2008 Summer;14(3):255-63. doi: 10.1162/artl.2008.14.3.14302. Artif Life. 2008. PMID: 18489251
-
Theoretical approaches to the evolution of development and genetic architecture.Ann N Y Acad Sci. 2008;1133:67-86. doi: 10.1196/annals.1438.002. Ann N Y Acad Sci. 2008. PMID: 18559816 Review.
-
Studying phenotypic evolution using multivariate quantitative genetics.Mol Ecol. 2006 Apr;15(4):883-96. doi: 10.1111/j.1365-294X.2006.02809.x. Mol Ecol. 2006. PMID: 16599954 Review.
-
Optimality models of phage life history and parallels in disease evolution.J Theor Biol. 2006 Aug 21;241(4):928-38. doi: 10.1016/j.jtbi.2006.01.027. Epub 2006 Apr 17. J Theor Biol. 2006. PMID: 16616205
Cited by
-
Food as exposure: Nutritional epigenetics and the new metabolism.Biosocieties. 2011 Jun;6(2):167-194. doi: 10.1057/biosoc.2011.1. Epub 2011 Mar 7. Biosocieties. 2011. PMID: 23227106 Free PMC article.
-
The new chimeric chiron genes evolved essential roles in zebrafish embryonic development by regulating NAD+ levels.Sci China Life Sci. 2021 Nov;64(11):1929-1948. doi: 10.1007/s11427-020-1851-0. Epub 2021 Jan 27. Sci China Life Sci. 2021. PMID: 33521859
-
Automated annotation of developmental stages of Drosophila embryos in images containing spatial patterns of expression.Bioinformatics. 2014 Jan 15;30(2):266-73. doi: 10.1093/bioinformatics/btt648. Epub 2013 Dec 3. Bioinformatics. 2014. PMID: 24300439 Free PMC article.
-
Gap Gene Regulatory Dynamics Evolve along a Genotype Network.Mol Biol Evol. 2016 May;33(5):1293-307. doi: 10.1093/molbev/msw013. Epub 2016 Jan 21. Mol Biol Evol. 2016. PMID: 26796549 Free PMC article.
-
Maternal co-ordinate gene regulation and axis polarity in the scuttle fly Megaselia abdita.PLoS Genet. 2015 Mar 10;11(3):e1005042. doi: 10.1371/journal.pgen.1005042. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25757102 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
