Acute hepatitis induced by an Aloe vera preparation: a case report

World J Gastroenterol. 2005 Jan 14;11(2):303-4. doi: 10.3748/wjg.v11.i2.303.


Aim: Aloe vera, plant extracts of Aloe barbadensis miller, is widely used in phytomedicine. The first case of acute hepatitis due to this compound was described.

Methods: Description of a clinical case.

Results: Hepatitis in a 57-year old female could be linked to the ingestion of Aloe barbadensis miller compounds. The patient's hepatitis resolved completely after discontinuing this medication.

Conclusion: The case emphasizes the importance of considering phytopharmaceutical over-the-counter drugs as causative agents of hepatitis.

Publication types

  • Case Reports

MeSH terms

  • Alanine Transaminase / blood
  • Aloe*
  • Aspartate Aminotransferases / blood
  • Female
  • Hepatitis / etiology*
  • Hepatitis / pathology
  • Hepatitis / therapy
  • Humans
  • Middle Aged
  • Nonprescription Drugs / adverse effects
  • Phytotherapy / adverse effects*


  • Nonprescription Drugs
  • Aspartate Aminotransferases
  • Alanine Transaminase