Progress of brown tumors in patients with chronic renal insufficiency undergoing dialysis

Eur J Radiol. Jan-Feb 1992;14(1):67-71. doi: 10.1016/0720-048x(92)90066-i.


In a group of 73 patients, affected by chronic renal insufficiency, whose skeleton was periodically checked, three cases of brown tumors were found. These cases demonstrated a variety of locations that were involved, especially the pelvis, ribs and mandible. During therapeutic treatment the brown tumors presented a different behavior; while some lesions tended toward complete sclerosis, others increased in size and in both instances new lesions appeared. Parathyroidectomy, carried out in two patients, determined a definitive sclerosis of these lesions. Brown tumors also correlate with high PTH levels and with lesions from osteitis fibrosa.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bone Diseases / diagnostic imaging*
  • Bone Diseases / pathology
  • Female
  • Follow-Up Studies
  • Granuloma, Giant Cell / diagnostic imaging*
  • Granuloma, Giant Cell / pathology
  • Humans
  • Kidney Failure, Chronic / diagnostic imaging*
  • Kidney Failure, Chronic / pathology
  • Kidney Failure, Chronic / therapy*
  • Male
  • Middle Aged
  • Osteitis Fibrosa Cystica / diagnostic imaging
  • Osteitis Fibrosa Cystica / pathology
  • Osteolysis / diagnostic imaging
  • Osteolysis / pathology
  • Osteosclerosis / diagnostic imaging
  • Osteosclerosis / pathology
  • Radiography
  • Renal Dialysis*
  • Retrospective Studies