Magnetic resonance imaging findings in Leber's hereditary optic neuropathy

Eur Neurol. 1992;32(1):17-9. doi: 10.1159/000116781.


The authors describe magnetic resonance imaging (MRI) findings in 15 subjects with different clinical stages of Leber's disease. A few and no characteristic abnormalities of the optic nerve signal were found. Nevertheless, MRI can be considered as a useful tool to differentiate optic neuritis together with visual and brainstem auditory evoked potentials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Diagnosis, Differential
  • Evoked Potentials, Visual / physiology
  • Female
  • Genetic Carrier Screening
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Optic Atrophies, Hereditary / diagnosis*
  • Optic Atrophies, Hereditary / genetics
  • Optic Nerve / pathology