Hypercalcemia caused by iatrogenic hypervitaminosis A

J Am Diet Assoc. 2005 Jan;105(1):119-21. doi: 10.1016/j.jada.2004.10.006.

Abstract

Vitamin A toxicity produces protean clinical manifestations involving a wide variety of tissues and systems. Hypercalcemia can occasionally be associated with high vitamin A levels, but is rare. In this report we describe a patient who was receiving a commercially prepared enteral feeding formula for 2 years. He developed asymptomatic hypercalcemia and had serum vitamin A levels several fold above normal. Subsequently, a custom-made enteral feed was used which contained negligible amounts of vitamin A. Several months later, vitamin A levels diminished substantially and serum calcium levels returned to normal.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Enteral Nutrition / adverse effects*
  • Humans
  • Hypercalcemia / blood
  • Hypercalcemia / etiology*
  • Hypervitaminosis A / blood
  • Hypervitaminosis A / complications*
  • Iatrogenic Disease*
  • Male
  • Miller Fisher Syndrome / therapy
  • Vitamin A / administration & dosage
  • Vitamin A / blood

Substances

  • Vitamin A