The desmoplastic melanocytic naevus: a distinct histological entity

Histopathology. 1992 Mar;20(3):207-11. doi: 10.1111/j.1365-2559.1992.tb00958.x.


Fifteen cases of desmoplastic melanocytic naevi are described in 12 female and three male patients, ranging in age from 8 to 83 years. The commonest site for the lesions was the upper limb. The lesions were characterized by a dense sclerotic or desmoplastic appearance of the dermal collagen surrounding a population of predominantly epithelioid naevus cells, some of which had a bizarre but non-malignant cytology. The cause of the stromal change is not established. We suggest that these lesions constitute a discrete entity which should be described in standard textbooks of dermatopathology.

MeSH terms

  • Adult
  • Aged
  • Child
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Male
  • Middle Aged
  • Nevus, Pigmented / chemistry
  • Nevus, Pigmented / pathology*
  • Skin Neoplasms / chemistry
  • Skin Neoplasms / pathology*