Enantioselective synthesis of chiral sulfinates using chiral diamines

Shuichi Nakamura; Motoaki Tateyama; Hideki Sugimoto; Masaya Nakagawa; Yoshihiko Watanabe; Norio Shibata; Takeshi Toru

doi:10.1002/chir.20112

Enantioselective synthesis of chiral sulfinates using chiral diamines

Chirality. 2005 Feb;17(2):85-8. doi: 10.1002/chir.20112.

Authors

Shuichi Nakamura¹, Motoaki Tateyama, Hideki Sugimoto, Masaya Nakagawa, Yoshihiko Watanabe, Norio Shibata, Takeshi Toru

Affiliation

¹ Department of Applied Chemistry, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan.

PMID: 15641116
DOI: 10.1002/chir.20112

Abstract

The reaction of p-toluenesulfinyl chloride with alcohols in the presence of chiral diamines was examined. Chiral sulfinates were obtained in good yields with enantioselectivity up to 76% ee.