[Influence of Eqb 761 on the function of the retina in children and adolescent with long lasting diabetes mellitus--preliminary report]

Klin Oczna. 2004;106(4-5):569-71.
[Article in Polish]


Purpose: Early detection of patological function of the retina, before anatomical changes, plays very important role in monitoring of visual complications in patients with diabetes mellitus. The aim of the study was the evaluation of anatomical and functional changes in visual organ in children and adolescents with long lasting diabetes mellitus type 1 and taking Egb 761 (Tanakan Beaufour Ipsen) as an adjuvant.

Materials and methods: Group consists of 15 patients, age between 11 and 19 years, with diabetes mellitus lasting 6-12 years. All patients had full ophthalmologic examination and color vision tests (Panel D 15 saturated and desaturated). The examination was done 3 times, every 3 months. Egb 761 was given: 1 tablet - 3 times a day, during 3 months.

Results: No diabetic retinopathy was found. The results of color vision test were better after therapy (25% of pathological results) and 3 months later (only 4 % of patients).

Conclusions: 1. Egb 761 seems to be good adjuvant in patient with long lasting diabetes mellitus. 2. Color vision tests are sensitive tests of the retinal function and are easy to perform.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Color Perception / drug effects
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetic Retinopathy / diagnosis*
  • Diabetic Retinopathy / etiology*
  • Drug Administration Schedule
  • Ginkgo biloba
  • Humans
  • Phytotherapy*
  • Plant Extracts / therapeutic use*
  • Retina / drug effects*
  • Retina / physiopathology


  • Plant Extracts
  • Ginkgo biloba extract