ProtTest: Selection of Best-Fit Models of Protein Evolution

Bioinformatics. 2005 May 1;21(9):2104-5. doi: 10.1093/bioinformatics/bti263. Epub 2005 Jan 12.

Abstract

Summary: Using an appropriate model of amino acid replacement is very important for the study of protein evolution and phylogenetic inference. We have built a tool for the selection of the best-fit model of evolution, among a set of candidate models, for a given protein sequence alignment.

Availability: ProtTest is available under the GNU license from http://darwin.uvigo.es

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Amino Acid Sequence
  • Amino Acid Substitution / genetics
  • Amino Acids / chemistry*
  • Amino Acids / genetics*
  • Computer Graphics
  • Computer Simulation
  • DNA Mutational Analysis / methods
  • Evolution, Molecular*
  • Humans
  • Internet
  • Models, Genetic*
  • Models, Molecular*
  • Molecular Sequence Data
  • Mutagenesis, Site-Directed / genetics
  • Phylogeny
  • Proteins / chemistry*
  • Proteins / genetics*
  • Sequence Analysis, Protein / methods*
  • Software
  • Structure-Activity Relationship
  • User-Computer Interface

Substances

  • Amino Acids
  • Proteins