Abstract
From the stem wood of Erythrina latissima, two isoflavones and a flavanone were isolated and characterized as 7,3'-dihydroxy-4'-methoxy-5'-(gamma,gamma-dimethylallyl)isoflavone (erylatissin A), 7,3'-dihydroxy-6'',6''-dimethyl-4'',5''-dehydropyrano [2'',3'': 4',5']isoflavone (erylatissin B), (-)-7,3'-dihydroxy-4'-methoxy-5'-(gamma,gamma-dimethylallyl)flavanone (erylatissin C), respectively, in addition to 10 known flavonoids. Structures of these compounds were determined on the basis of their spectroscopic data. These compounds showed antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Candida mycoderma. The isolated compounds also exhibited weak radical scavenging properties towards DPPH radical.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / isolation & purification
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Biphenyl Compounds
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Erythrina / chemistry*
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Flavanones / chemistry
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Flavonoids / chemistry*
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Flavonoids / isolation & purification
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Flavonoids / pharmacology
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification
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Isoflavones / chemistry
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Molecular Structure
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Picrates / chemistry
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Plant Stems / chemistry*
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Wood
Substances
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7,3'-dihydroxy-4'-methoxy-5'-(gamma,gamma-dimethylallyl)flavanone
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7,3'-dihydroxy-4'-methoxy-5'-(gamma,gamma-dimethylallyl)isoflavone
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7,3'-dihydroxy-6'',6''-dimethyl-4'',5''-dehydropyrano(2'',3'': 4',5')isoflavone
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Anti-Infective Agents
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Biphenyl Compounds
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Flavanones
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Flavonoids
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Free Radical Scavengers
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Isoflavones
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Picrates
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1,1-diphenyl-2-picrylhydrazyl