Anaphylactic reaction to inulin: first identification of specific IgEs to an inulin protein compound

Int Arch Allergy Immunol. 2005 Feb;136(2):155-8. doi: 10.1159/000083323. Epub 2005 Jan 12.


Background: A woman with a past history of allergy to artichoke presented with two episodes of immediate allergic reactions, one of which was a severe anaphylactic shock after eating two types of health foods containing inulin.

Results: Dot blot assay techniques identified specific IgEs to artichoke, to yoghurt F, and to a heated BSA + inulin product. Dot blot inhibition techniques confirmed the anti-inulin specificity of specific IgE.

Conclusions: The absence of a positive reaction to an unheated milk-inulin mixture indicates the probability of protein-inulin binding. There is no cross-reactivity with the carbohydrates of the glycosylated allergens.

Publication types

  • Case Reports

MeSH terms

  • Anaphylaxis / immunology*
  • Cynara scolymus / adverse effects
  • Cynara scolymus / immunology
  • Female
  • Food, Organic / adverse effects
  • Humans
  • Immunoblotting
  • Immunoglobulin E / immunology*
  • Inulin / adverse effects*
  • Inulin / immunology
  • Middle Aged
  • Yogurt / adverse effects


  • Immunoglobulin E
  • Inulin