Treatment intensity and outcome of patients aged 80 and older in intensive care units: a multicenter matched-cohort study

J Am Geriatr Soc. 2005 Jan;53(1):88-93. doi: 10.1111/j.1532-5415.2005.53016.x.


Objectives: To determine whether patients aged 80 and older have similar treatment intensity to that of younger patients in the intensive care unit (ICU).

Design: Multicenter, matched-cohort study.

Setting: Data were extracted from a multicenter database with 36 ICUs in the Paris area (France) during a 4-year period (1997-2000).

Participants: Three thousand one hundred seventy-five patients aged 80 and older (oldest-old) were retrospectively matched to 3,175 patients aged 65 to 79 (young-old).

Measurements: The matching criteria were severity status on admission (+/-2) (assessed using a corrected Simplified Acute Physiology Score II leaving out age points), Charlson Comorbidity Index, type of admission (surgical vs medical), sex, admission to same ICU, and year of ICU admission. The underlying condition was classified using the McCabe classification. The functional status was assessed using the Knaus classification. The ICU workload was assessed using the OMEGA scoring system.

Results: Total and daily workload were lower in the oldest-old than in matched young-old patients. Estimated mean direct medical cost per stay was approximately 1,280 dollars lower for oldest-old patients. Older patients received less mechanical ventilation (adjusted odds ratio (AOR)=0.69, 95% confidence interval (CI)=0.61-0.78), less tracheostomy (AOR=0.37, 95% CI=0.28-0.50), and less renal support (AOR=0.52, 95% CI=0.41-0.66) than matched young-old patients. Oldest-old patients had a shorter length of ICU stay than matched young-old patients and the same length of post-ICU stay.

Conclusion: Oldest-old patients receive less treatment in the ICU than young-old patients even after adjustment for severity of illness.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Female
  • France
  • Health Care Costs / statistics & numerical data
  • Health Services for the Aged / statistics & numerical data*
  • Humans
  • Intensive Care Units / statistics & numerical data*
  • Male
  • Odds Ratio
  • Respiration, Artificial
  • Retrospective Studies
  • Severity of Illness Index
  • Treatment Outcome