Long-term sequelae of acute pelvic inflammatory disease. A retrospective cohort study

Am J Obstet Gynecol. 1992 Apr;166(4):1300-5. doi: 10.1016/s0002-9378(11)90626-7.


Objective: Our objective was to prospectively assess the frequency and predictors of long-term sequelae of acute pelvic inflammatory disease.

Study design: We performed a retrospective cohort study of 140 women admitted for treatment of pelvic inflammatory disease to San Francisco General Hospital in 1985, locating and interviewing 51 women by telephone a median of 37 months later.

Results: Twelve (24%) women had pelvic pain for 6 months or more after hospitalization, 22 (43%) had subsequent episode(s) of pelvic inflammatory disease, and 40% were involuntarily infertile. A history of pelvic inflammatory disease prior to admission was associated with infertility (p = 0.05), chronic pelvic pain (p = 0.03), and pelvic inflammatory disease subsequent to hospitalization (p = 0.06). Longer duration of abdominopelvic pain before admission and younger age at the time of first sexual intercourse were associated with both infertility (p = 0.02, p = 0.04) and subsequent pelvic inflammatory disease (p = 0.04, p = 0.0008).

Conclusions: Further studies are needed to more accurately assess the incidence and predictors of long-term sequelae of pelvic inflammatory disease. A reduction in adverse outcome will require more stringent efforts at education and reduction of risk-taking behaviors.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acute Disease
  • Adult
  • Age Factors
  • Cohort Studies
  • Coitus
  • Female
  • Forecasting
  • Humans
  • Infertility, Female / etiology
  • Interviews as Topic
  • Pain
  • Pelvic Inflammatory Disease / complications*
  • Pelvic Inflammatory Disease / microbiology
  • Pelvic Inflammatory Disease / physiopathology
  • Pelvis
  • Retrospective Studies