Cortical thickness of the frontopolar area in typically developing children and adolescents

Neuroimage. 2005 Feb 15;24(4):948-54. doi: 10.1016/j.neuroimage.2004.10.014. Epub 2004 Dec 15.

Abstract

The development of the frontopolar cortex (FPC) through late childhood and adolescence was investigated using measures of cortical thickness. T(1)-weighted structural MRIs from 35 typically developing participants aged 8-20 years were used to construct 3D models of the brain, from which cortical thickness was measured. There was a significant inverse association between age and cortical thickness, such that cortical thickness decreased as age increased between 8 and 20 years. There was no effect of laterality or gender on cortical thickness.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aging / physiology
  • Cerebral Cortex / anatomy & histology
  • Cerebral Cortex / growth & development*
  • Child
  • Female
  • Frontal Lobe / anatomy & histology
  • Frontal Lobe / growth & development*
  • Functional Laterality / physiology
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Reference Values
  • Sex Characteristics
  • Visual Cortex / anatomy & histology
  • Visual Cortex / growth & development