Correlation between anthropometrics measurements, prealbumin level and transferin serum with Child-Pugh classification in evaluating nutritional status of liver cirrhosis patient

Acta Med Indones. 2004 Oct-Dec;36(4):197-201.

Abstract

Aim: to evaluate nutritional status by using anthropometrics and biochemistry examination and to determine the correlation between albumin, prealbumin and transferin serum level with anthropometrics measures in liver cirrhosis patient according to Child-Pugh classification.

Methods: study was conducted on 30 patients with liver cirrhosis Child-Pugh A, B and C. There were 8 patient of Child-Pugh A, 18 Child-Pugh B and 4 Child-Pugh C. Every patient underwent anthropometrics and biochemistry examination including ideal body weight (IBW), body mass index (BMI), triceps skin-fold thickness (TSF), mid-arm circumference (MAC), mid-arm muscle circumference (MAMC), albumin, prealbumin and transferin serum. We used statistical analysis Spearman and Pearson correlation test.

Results: by IBW and BMI measurement, most of liver cirrhosis patients indicated normal results. By MAMC measurement, there was no liver cirrhosis patient with good nutritional status. Most of them have slight and moderate malnutrition. There was no significant correlation between anthropometrics measurement with Child-Pugh score, with [p > 0.01]. And also, there was no significant relationship between albumin, prealbumin and serum transferin with anthropometrics measures, but there was significant correlation between prealbumin and transferin level with Child-Pugh score, with [p < 0.01].

Conclusion: the conclusion of this study is prealbumin and transferin level may be used to evaluate nutritional status of liver cirrhosis patient, and on the contrary with anthropometrics measures. There was no correlation between anthropometrics measures with albumin, prealbumin and transferin level.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Anthropometry / methods
  • Biomarkers / blood
  • Body Mass Index
  • Body Weights and Measures / statistics & numerical data*
  • Comorbidity
  • Female
  • Humans
  • Indonesia / epidemiology
  • Liver Cirrhosis / blood*
  • Liver Cirrhosis / classification*
  • Liver Cirrhosis / epidemiology
  • Liver Cirrhosis / physiopathology
  • Male
  • Malnutrition / blood
  • Malnutrition / epidemiology
  • Malnutrition / physiopathology
  • Middle Aged
  • Nutrition Assessment*
  • Prealbumin / analysis*
  • Skinfold Thickness
  • Transferrin / analysis*

Substances

  • Biomarkers
  • Prealbumin
  • Transferrin