Autonomic dysfunction in tetanus: the effects of a variety of therapeutic agents, with special refernce to morphine

Intensive Care Med. 1979 May;5(2):65-8. doi: 10.1007/BF01686048.


Sympathetic overactivity in tetanus is a common event and may be difficult to control. This report demonstrates the efficacy of morphine in this clinical situation and also discusses the sympathetic effects of 3 muscle relaxants, pancuronium, d-tubocurarine and alcuronium.

MeSH terms

  • Adult
  • Autonomic Nervous System / physiopathology*
  • Diazepam / therapeutic use
  • Humans
  • Morphine / therapeutic use*
  • Nervous System Diseases / drug therapy*
  • Neuromuscular Nondepolarizing Agents / therapeutic use
  • Tetanus / complications
  • Tetanus / drug therapy
  • Tetanus / physiopathology*


  • Neuromuscular Nondepolarizing Agents
  • Morphine
  • Diazepam