Oxygen saturation during sleep in patients with bronchopulmonary dysplasia

Biol Neonate. 1992;61(2):69-75. doi: 10.1159/000243533.


We hypothesized that significant sleep desaturation might occur in infants with bronchopulmonary dysplasia whose awake saturations were between 90 and 92%. Supplemental oxygen was continued until the awake saturation on room air was 90% or greater. Sleep saturations were monitored by oximetry sampling for a 3-min period every hour overnight. Significant desaturation was considered to be present if the saturation fell repeatedly below 88%. There were 39 studies performed in room air, and 14 studies in supplemental oxygen. We demonstrated that patients with acceptable awake saturation may desaturate while sleeping. However, only 1 of 25 patients whose saturation in room air was 92% or more repeatedly desaturated during sleep.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bronchopulmonary Dysplasia / blood
  • Bronchopulmonary Dysplasia / physiopathology*
  • Bronchopulmonary Dysplasia / therapy
  • Child, Preschool
  • Humans
  • Infant
  • Infant, Newborn
  • Oxygen / blood*
  • Oxygen / therapeutic use
  • Retrospective Studies
  • Sleep / physiology*
  • Wakefulness / physiology


  • Oxygen