Mycoplasma genitalium: an organism commonly associated with cervicitis among west African sex workers

Sex Transm Infect. 2005 Feb;81(1):67-72. doi: 10.1136/sti.2003.009100.


Objectives: To identify the contribution of Mycoplasma genitalium to the aetiology of cervicitis in sub-Saharan Africa and its relative importance in the overall burden of sexually transmitted infections among female sex workers (FSW).

Methods: The study population consisted of FSW recruited in Ghana and Benin during the initial visit of a randomised controlled trial. A questionnaire was administered, a pelvic examination carried out, and cervical samples obtained for detection of M genitalium, Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis. Clinical signs potentially indicating cervicitis were cervical discharge, pus on the cervical swab, bleeding after sampling, and inflammatory cervix.

Results: Among 826 FSW, 26.3% were infected with M genitalium. N gonorrhoeae was strongly and independently associated with each of the four signs of cervicitis (adjusted odds ratios (AOR): 4.1 to 6.0). The AOR for C trachomatis were intermediate (1.3-4.1) and the AOR for M genitalium were lower (between 1.6 and 1.8) but statistically significant (p< or =0.05) for each sign.

Conclusions: M genitalium is weakly associated with signs of cervicitis in west African FSW but is highly prevalent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Benin / epidemiology
  • Chlamydia Infections / epidemiology
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Ghana / epidemiology
  • Gonorrhea / epidemiology
  • Humans
  • Middle Aged
  • Mycoplasma Infections / drug therapy
  • Mycoplasma Infections / epidemiology*
  • Mycoplasma genitalium*
  • Polymerase Chain Reaction / methods
  • Risk Factors
  • Sex Work*
  • Trichomonas Infections / epidemiology
  • Uterine Cervicitis / microbiology*


  • Anti-Bacterial Agents