[Dynamics of calcium intake in the brain tissue in hypercholesterolemia]

Fiziol Zh. 2004;50(5):43-9.
[Article in Ukrainian]

Abstract

A dynamics of calcium content in rat brain during endogenic hypercholesterolemia, caused by action of the stressful factor (restriction of vital space (80-100 sm2 per one individual) and high salt diet (2 g/kg)) was studied. It was revealed that under the given conditions there is an increase in calcium content in the brain. Nifedipine (2 mg/ kg per day) significantly reduced calcium content in the brain that has allowed making an assumption of some mechanisms of this phenomenon.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Brain / metabolism*
  • Calcium / metabolism*
  • Cholesterol / blood
  • Disease Models, Animal
  • Hypercholesterolemia / etiology
  • Hypercholesterolemia / metabolism*
  • Nifedipine / pharmacology
  • Rats
  • Stress, Psychological / complications

Substances

  • Cholesterol
  • Nifedipine
  • Calcium