Hydroxymethyldihydropterin pyrophosphokinase from Plasmodium falciparum complements a folK-knockout mutant in E. coli when expressed as a separate polypeptide detached from dihydropteroate synthase

Mol Biochem Parasitol. 2005 Mar;140(1):123-5. doi: 10.1016/j.molbiopara.2004.11.016.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Dihydropteroate Synthase / metabolism*
  • Diphosphotransferases / genetics
  • Diphosphotransferases / metabolism*
  • Escherichia coli / genetics
  • Escherichia coli / metabolism
  • Gene Deletion
  • Gene Expression
  • Multienzyme Complexes / genetics
  • Plasmodium falciparum / enzymology*
  • Plasmodium falciparum / genetics
  • Tetrahydrofolate Dehydrogenase / genetics
  • Thymidylate Synthase / genetics

Substances

  • Multienzyme Complexes
  • thymidylate synthase-dihydrofolate reductase
  • Tetrahydrofolate Dehydrogenase
  • Thymidylate Synthase
  • Dihydropteroate Synthase
  • Diphosphotransferases
  • 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase