Effect of early initiation of statins on survival in patients with acute myocardial infarction (the USIC 2000 Registry)

Am J Cardiol. 2005 Feb 15;95(4):486-9. doi: 10.1016/j.amjcard.2004.10.016.

Abstract

We evaluated the association of statin initiation within 48 hours of admission for an acute myocardial infarction with a 1-year prognosis on a nationwide scale. Patients who received a statin within 48 hours of admission but not before hospitalization had an improved prognosis (hazard ratio 0.57, 95% confidence interval 0.38 to 0.86, p <0.007) after adjustment for covariates and propensity score.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Female
  • France / epidemiology
  • Hospitalization*
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*
  • Intensive Care Units
  • Male
  • Middle Aged
  • Myocardial Infarction / drug therapy*
  • Myocardial Infarction / mortality*
  • Prognosis
  • Proportional Hazards Models
  • Registries
  • Time Factors

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors