[A novel translocation t(1;18)(p31;p11) in a patient with myelodysplastic syndrome]

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Feb;22(1):74-5.
[Article in Chinese]

Abstract

Objective: To report a case of myelodysplastic syndrome(MDS) with t(1;18)(p31;p11).

Methods: Chromosome specimens were prepared by short-term culture of bone marrow cells. Karyotype analysis was made by R banding technique. Chromosome painting was performed using whole chromosome probes 1 and 18.

Results: Conventional karyotype analysis revealed t(1;18)(p31;p11) in this patient. Chromosome painting analysis confirmed this result.

Conclusion: The translocation of (1;18) was an unusual recurrent chromosome change and was reported on MDS for the first time.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Chromosomes, Human, Pair 1*
  • Chromosomes, Human, Pair 18*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Karyotyping
  • Male
  • Myelodysplastic Syndromes / genetics*
  • Translocation, Genetic / genetics*