Hydrolysis of acetylcholinesterase inhibitors--organophosphorus acid anhydrolase enzyme immobilization on photoluminescent porous silicon platforms

Chem Commun (Camb). 2005 Feb 21:(7):851-3. doi: 10.1039/b412215a. Epub 2004 Dec 23.

Abstract

We report on the immobilization of an OPAA enzyme on luminescent porous silicon devices, and on the utilization of this new platform to hydrolyze p-nitrophenyl-soman.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aryldialkylphosphatase / chemistry*
  • Cholinesterase Inhibitors / chemistry*
  • Enzymes, Immobilized
  • Hydrolysis
  • Molecular Structure
  • Porosity
  • Silicon / chemistry*
  • Soman / analogs & derivatives
  • Soman / chemistry*
  • Surface Properties
  • Time Factors

Substances

  • Cholinesterase Inhibitors
  • Enzymes, Immobilized
  • Soman
  • Aryldialkylphosphatase
  • Silicon